CAS Number

155270-99-8

Molecular Formula

Molecular Weight

384.43

Molecular Structure

Packing

1/5/10kg/drum

Capacity

200kg/M

Storage

Sealed tightly and stored away from light in a cool and dry place

Application

Istradefylline is a medication used as an add-on treatment to levodopa/carbidopa in adults with Parkinson's disease (PD) experiencing "off" episodes.[2][3][4] Istradefylline reduces "off" periods resulting from long-term treatment with the antiparkinson drug levodopa.[2] An "off" episode is a time when a patient's medications are not working well, causing an increase in PD symptoms, such as tremor and difficulty walking.

Appearance

yellowish green crystalline powder

  Identification

I.R. Should be consistent with the reference map

Ultraviolet Maximum absorption at 226nm and 360nm 

Chemical Positive reaction

  Loss on Drying

≤0.5%

  Residue on Ignition

≤0.02%  

  Chromatographic Purity

Impurity A≤0.1%  

                             Cyanoacetic acid: ≤0.02%

                             Glacial acetic acid: ≤0.1%

                             Single impurity≤0.1%

                             Total Impurities≤0.5%

 Particle Size

D90 ≤100 Microns

 Assay(on dried basis)

 98.0 ～ 102.0%

Standard

In-house standard