A protected serine amino acid peptide building block. ComWin supplies Fmoc-Ser(tBu)-OH for the solid-phase peptide synthesis of therapeutic peptides, bioactive protein fragments, and custom Fmoc-based peptide intermediates.
This protected amino acid delivers orthogonal dual-group protection and eliminates side O-acylation reactions for high-fidelity peptide assembly. It is a critical Fmoc/tBu building block for therapeutic peptide APIs, bioactive signaling fragments, and complex custom peptide intermediates.
| Chemical Name | Fmoc-Ser(tBu)-OH |
| CAS Number | 71989-33-8 |
| Molecular Formula | C22H25NO5 |
| Molecular Weight | 383.44 |
| Molecular Structure |  |
| Packing | 25kg/drum |
| Retest | 1 year |
| Items | Specifications |
| Appearance | White to off-white solid |
| Identification | by HNMR in accordance with structure |
| Solubility | 0.3g in 2ml DMF clearly solution |
| Water content (KF%) | ≤ 1.00% |
| Loss on drying | ≤ 1.00% |
| Purity (%) | ≥ 99.00% |
| Related substances1: HPLC Fmoc-β-Ala-OH Fmoc-OH Fmoc-OSU Maximum unknown single impurity | ≤ 0.10% ≤ 0.10% ≤ 0.10% ≤ 0.10% |
| Related substances 2: HPLC HOSU | ≤ 0.10% |
| Residual solvents: Ethyl acetate Petroleum ether Dichloromethane Methyl tert-butyl ether | ≤5000ppm ≤5000ppm ≤600ppm ≤5000ppm |
| D-enantiomer | ≤ 0.10% |
| De-Fmoc | ≤ 0.1% |
| Assay (by titration) | 98.00%-102.00% |
| Standard | In-House |
* The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The users are suggested to select the suitability of the products and methods of application.
Used in the assembly of therapeutic peptide APIs and long-chain bioactive peptides
Suitable for preparing lab-scale signaling peptide fragments and custom peptide intermediates.
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