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Ivermectin

Ivermectin is an antiparasite agent which can be absorbed by permeance from skin.

Model: 70288-86-7

Description

Antiparasitic drugs have anthelmintic activity against nematodes, hookworms, roundworms, helminths, insects, and mites.

Chemical Name22,23-dihydroavermectin B1a
CAS Number70288-86-7
Molecular FormulaC48H74O14
Molecular Weight875.09
Molecular Structure结构式
PackingDrum
CapacityProduction upon order
StorageKeep tightly closed in light-resistant containers.
ApplicationAntiparasitic drugs have anthelmintic activity against nematodes, hookworms, roundworms, helminths, insects, and mites.

Specification

ItemsSpecifications
AppearanceWhite or yellowish‑white crystalline powder, slightly hygroscopic
SolubilityPractically insoluble in water, freely soluble in methylene chloride, soluble in alcohol (96 per cent)
IdentificationMeet the requirements
Appearance of SolutionClear and not more intensely coloured than reference solution BY7
Specific Optical Rotation
(anhydrous and solvent‑free substance),°
-20 to -17
Water, %≤1.0
Heavy Metal, ppm≤20
Sulfated Ash, %≤0.1
Ethanol and Formamide, %Ethanol≤5.0
Formamide ≤3.0
Related Substances, %Individual Impurity (RRT1.3‑1.5) ≤2.5
Any Other Impurity ≤1
Total Impurity ≤5
Disregard Limit: 0.05
Assay (anhydrous and solvent‑free substance), %Ratio H₂B1ₐ/(H₂B1ₐ +H₂B1b)≥ 90.0
95.0≤Ivermectin (H₂B1ₐ +H₂B1b) ≤102.0
StandardEP11.0

* The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The users are suggested to select the suitability of the products and methods of application.

Key Applications

Oral Formulations

Used in the production of tablets, and oral solutions.

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