Losartan Potassium API CAS 124750-99-8 USP EP Grade ARB Raw Material

Human APIs

Losartan Potassium

USP/EP grade Angiotensin II Receptor Blocker (ARB) salt. ComWin ensures consistent particle size distribution for the efficient production of antihypertensive tablets and capsules.

Model: CAS NO.: 124750-99-8

Request your customized solution

Description

Losartan Potassium is the potassium salt of losartan, a non-peptide angiotensin II receptor antagonist with high selectivity for the AT1 receptor. It exhibits excellent stability and solubility profiles essential for generic drug development.

Chemical Name	Losartan Potassium
CAS Number	124750-99-8
Molecular Formula	C22H23ClKN6O
Molecular Weight	462.01
Molecular Structure
Packing	As Requested
Shelf-life	Three years
Storage Condition	Sealed storage
Application	Hypertension treatment, Diabetic nephropathy protection, Stroke risk reduction, Heart failure management

Specification

Items		Specifications
Appearance		White to almost white powder
Solubility		Freely soluble in water
		Slightly soluble in isopropanol
		Slightly soluble or very slightly soluble in acetonitrile
Identification	IR	IR spectrum complies with the spectrum of standard
	HPLC	The retention time of main peak in sample solution is consistent with in standard solution
	Potassium	Complies with the test in the test procedure
Water (KF)		≤ 0.5%
Related substances (HPLC)		Unspecified impurity ≤ 0.2%
		Total impurities ≤ 0.5%
Assay (HPLC)		98.5~101.0%, calculated on the anhydrous substance and solvent-free basis
Residual solvents (GC) Isopropanol		≤ 5000ppmx
Standard		USP Standard

* The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The users are suggested to select the suitability of the products and methods of application.