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Pentoxifylline

A xanthine derivative API utilized in hemorheological formulations. ComWin supplies grades suitable for controlled-release processing to ensure sustained therapeutic release profiles.

Model: CAS NO.: 6493-05-6

Description

Pentoxifylline is a synthetic dimethylxanthine derivative that improves blood flow properties. Its physicochemical characteristics make it suitable for various drug delivery systems, including extended-release matrices.


Chemical NamePentoxifylline
CAS Number6493-05-6
Molecular FormulaC13H18N4O3
Molecular Weight278.31
Molecular Structure3-己酮可可碱(1).jpg
PackingAs Requested
Shelf-lifeFour years
Storage ConditionRoom Temperature
ApplicationPeripheral vascular disease treatment, Intermittent claudication relief, Microcirculation improvement, Chronic venous ulcer adjunct

Specification

ItemsSpecifications
AppearanceWhite or almost white, crystalline powder
IdentificationMelting Point: 103~107℃
Infrared Absorption: Conforms to pentoxifylline CRS
Appearance of solutionClear and not more intensely coloured than reference solution Y7
Acidity≤ 0.2ml of 0.01M sodium hydroxide
Related SubstancesImpurities A, C, F≤ 0.1%
Impurity J≤ 0.1%
Any Other Impurity≤ 0.1%
Total Impurities≤ 0.5%
Chlorides≤ 100ppm
Sulphates≤ 200ppm
Loss on Drying≤ 0.5%
Sulphated ash≤ 0.1%
Assay99.0~101.0%
StandardEP Standard

* The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The users are suggested to select the suitability of the products and methods of application.

Key Applications

Sustained-Release Tablets

Key active ingredient for producing extended-release dosage forms.

Injectable Solutions

High-purity grade available for the manufacturing of parenteral infusion concentrates.

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