A versatile non-selective beta-blocker API. ComWin offers USP/BP/EP compliant Propranolol HCL, ideal for a wide range of cardiovascular and neurological dosage forms.
Propranolol Hydrochloride is a synthetic beta-adrenergic receptor blocking agent. It is a stable, white crystalline powder with well-defined solubility, making it a staple raw material in pharmaceutical compounding.
| Chemical Name | Propranolol Hydrochloride |
| CAS Number | 3506-09-0 |
| Molecular Formula | C16H22ClNO2 |
| Molecular Weight | 295.8 |
| Molecular Structure |  |
| Packing | 25KG/Drum |
| Shelf-life | Four years |
| Storage Condition | Room temperature |
| Application | Hypertension treatment, Cardiac arrhythmia management, Migraine prophylaxis, Essential tremor control |
| Items | Specifications |
| Appearance | White or almost white powder |
| Solubility | Soluble in water and in ethanol (96 %) |
| Practically insoluble in heptane | |
| Identification | IR. Test |
| Chlorides test(a) | |
| Appearance of solution | Clear and not more intensely coloured than intensity 6 |
| Acidity or alkalinity | Positive reaction |
| Related substances | Any other impurity≤ 0.1% |
| Total impurities≤ 0.2% | |
| Loss on drying | ≤ 0.5% |
| Sulfated ash | ≤ 0.1% |
| Residual solvent | Isopropamide≤ 0.1% |
| Triethylamine≤ 0.1% | |
| Ethanol≤ 0.5% | |
| Dimethylbenzene≤ 0.217% | |
| Assay | 99.0~101.0% |
| Standard | EP Standard |
* The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The users are suggested to select the suitability of the products and methods of application.
Used in the production of tablets, capsules, and oral solutions.
Suitable for processing into sterile injectable formulations.
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