Semaglutideis a glucagon-like peptide-1 (GLP-1) receptor agonist developed for the treatment of type 2 diabetes and chronic weight management. It works by enhancing glucose-dependent insulin secretion, reducing glucagon release, slowing gastric emptying, and increasing satiety, which helps improve blood glucose control and support weight loss.
Semaglutideis a glucagon-like peptide-1 (GLP-1) receptor agonist developed for the treatment of type 2 diabetes and chronic weight management..
| Chemical Name | Semaglutide |
| CAS Number | 910463-68-2 |
| Molecular Formula | C187H291N45O59 |
| Molecular Weight | 4113.57754 |
| Molecular Structure |  |
| Packing | 10G/Bottle, 100G/Bottle, 500G/Bottle |
| Shelf-life | Two years |
| Storage Condition | Preserve in a tight, light-resistant containers at a temperature 2~8ºC |
| Application | Type 2 diabetes management Chronic weight management in eligible adults Cardiometabolic risk reduction in appropriate patient populations |
| Items | Specifications |
| Appearance | White or off-white powder |
| Solubility | Freely soluble in water |
| MS (ESI) | 4113.64±1.0 |
| Purity(HPLC) | ≥99.0% |
| Related Substance (HPLC) | Any individual impurity≤0.7% Total related substances≤1.0% |
| Peptide Content | ≥85.0% |
| Water Content (Karl Fischer) | ≤10.0% |
| PH(5.0MG/ML) | 6.0-8.0 |
| Amino Acid analysis | Asp, His, Tyr, Lys, Ile, Leu, Val, Arg, Thr, Phe, Ser, Ala, Gly, Glu |
| Sodium | <5.0% |
| Polymer | ≤ 0.3% |
| Residual solvents | Isopropyl alcohol NMT 5000ppm Acetonitrile NMT 410ppm Dichloromethane NMT 600ppm Methyl tert-butyl ether NMT 5000ppm Methanol NMT 3000ppm N,N-Dimethylformamide NMT 880ppm |
| Bacterial endotoxins | <10EU/mg |
| Microbial Limits | Total aerobic microbial count ≤200cfu/g Total yeast and mold count ≤200cfu/g |
| Assay(HPLC) | 95.0~105.0% (on anhydrous and salt-free substance basis) |
| Standard | In-House Standard |
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