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Ledipasvir CAS No 1256388-51-8
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LEDIPASVIR(ACETONE)
| Chemical Name | Ledipasvir(acetone) |
| CAS Number Molecular Formula Molecular Weight | 1441674-54-9 C49H54F2N8O6.C3H6O 947.08 |
| Molecular Structure |  |
| Packing | 20kg/drum |
| Storage | Store in a tightly sealed container away from heat and direct light, and in a cool dry place. |
| Application | Ledipasvir is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. |
SPECIFICATION
| Items | Specification |
| Appearance | Off-white to white powder |
| Identification | Meet the Requirements |
| Polymorphic Identity | XRD |
| Loss on Drying | ≤7.13% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals | ≤0.002% |
| Palladium | ≤10ppm |
| Impurity (by HPLC) | LPS-8≤0.15% |
| LPS-B≤0.15% | |
| LPS-C≤0.15% | |
| LPS-D≤0.15% | |
| LPS-D2≤0.15% | |
| LPS-one≤0.15% | |
| Any unknown impurity≤0.10% | |
| Total impurities≤1.0% | |
| Residue Solvents | Isopropy acetate ≤5000 ppm |
| Ethyl acetate ≤5000 ppm | |
| 61324ppm≤acetone≤66324 ppm | |
| N,N-Dimethyl formamide≤880 ppm | |
| 1,4-dioxane≤380 ppm | |
| 1,2-dimethoxyethane≤100 ppm | |
| Assay | 98.0%~102.0% |
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