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Trimebutine Maleate

An antispasmodic and gastrointestinal motility regulator used to relieve abdominal pain and symptoms associated with functional bowel disorders.

Model: 34140-59-5

Description

An antispasmodic and gastrointestinal motility regulator used to relieve abdominal pain and symptoms associated with functional bowel disorders.


TRIMEBUTINE MALEATE
Chemical Name3,4,5-trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester maleate
CAS Number34140-59-5
Molecular FormulaC₂₆H₃₃NO₉
Molecular Weight503.54
Molecular StructureTrimebuty.jpg
Packing25kg/drum
StorageKeep in well-closed containers, protected from light.
ApplicationAn antispasmodic and gastrointestinal motility regulator used to relieve abdominal pain and symptoms associated with functional bowel disorders.

Specification

ItemsSpecifications
AppearanceWhite or almost white crystalline powder
IdentificationIR test
SolubilitySlightly soluble in water, soluble in acetonitrile, sparingly soluble in acetone, Slightly soluble in ethanol(96%)
Melting PointAbout 133℃
Appearance of solutionClear and colorless
Loss on drying≤0.5%
Sulfated Ash≤0.1%
Related SubstancesImpurity E ≤0.6%
Unspecified impurity ≤0.10%
Total impurities ≤1.0%
Residual SolventMethanol ≤0.3%
Ethanol ≤0.5%
Tetrahydrofuran ≤0.072%
Toluene ≤0.089%
Microbial CountBacteria<1000cfu/g
Yeast and Mould<100cfu/g
E.Coli: absent/g
Particle SizeD(90)<150μm
Assay (On the dried basis)99.0%-101.5%
StandardEP

* The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The users are suggested to select the suitability of the products and methods of application.

Key Applications

Oral Gastrointestinal Preparations

Used for manufacturing tablets and capsules to regulate gut motility.

Functional Bowel Disorder Treatment

Applied to alleviate abdominal pain, bloating and irritable bowel symptoms.

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