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Polysulfated Glycosaminoglycan
Contact us Product DetailsPolysulfated-Glycosaminoglycan (PSGAG) is mostly used in dogs and horses for treating traumatic arthritis and degenerative joint disease (osteoarthritis). It has shown to be better at treating acute than chronic arthritis, though some studies say that its effectiveness in acute cases is still limited if degenerative enzymes haven't played a role. While it is currently only FDA-approved for dogs and horses, PSGAG is also used off-label to treat lameness in swine, as a chondroprotectant ("joint protector") or treatment of interstitial cystitis in cats, and to treat arthritis in rabbits.
Items | Specification |
Characters | White to yellowish white powder |
Identification | The retention time of the major peak of the sample preparation corresponds to that of standard preparation. Sulfate/carboxylate Ratio: 2.5-4.0 Sodium: Positive Toluidine Blue O Reaction: Positive |
Specific Rotation | Between -8.0︒ and -15.0︒ |
Molecular Weight and Molecular Weight distribution | Mw:7300-9300 PDI:1.0-1.5 |
PH | 5.5-8.0 |
Glucuronic Acid | 18.0%-25.0% |
Nucleotides | NMT0.2% |
Nitrogen | 1.5%-2.5% |
Related substances | Chondroitin Sulfate by HPLC: NMT5.0% |
Unspecified Impurity: Individual: NMT0.20% Total: NMT1.0% | |
Residual Solvent（Ethanol） | NMT 5000ppm |
Acetic Acid | NMT 5000ppm |
Free Sulfate | NMT 5.0% |
Loss on Drying | NMT 5.0% |
Residue on Ignition | 38.0% - 48.0% |
Heavy Metals | NMT 20ppm |
Microbiological Examination | Total aerobic microbial count: NMT 103 cfu/g Total combined yeasts/molds count: NMT102 cfu/g |
Bacterial Endotoxins | NMT2.5 EU/mg |
Content | NLT 85.0% (on the dried basis) |
Standard | In-house |
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