Safety Data Sheet
According to Regulation (EU) No. 1907/2006 (REACH), Annex II
Version: 1.0/EN Revision date: 26/12/2022
Product name: Minoxidil Sulphate
Printing date: 13/01/2023
Section 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier Substance name: Minoxidil Sulphate；Minoxidil Sulfate
REACH Reg. No.: Not applicable.
CAS No.: 83701-22-8 EC No.: 635-997-7
1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses: Active Pharmaceutical Ingredients. Uses advised against: Not available.
1.3 Details of the supplier of the SDS Manufacturer: Changzhou ComWin Fine Chemicals Co.,Ltd. Address: 24th Floor, Jiaye International Commercial Plaza 99 Yanling West Road, Changzhou Jiangsu 213003 China E-mail: email@example.com Telephone: + 0086 519 8661 9955 Fax: + 0086 519 8681 6696 1.4 Emergency telephone number In China: +0086 519 8661 9955 (Office hours available)
Section 2: Hazards identification
2.1 Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 4), H302
Skin irritation (Category 2), H315
Eye irritation (Category 2A), H319
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 GHS Label elements, including precautionary statements
Signal word Warning
H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P301 + P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312 Call a POISON CENTER/doctor if you feel unwell.
P321 Specific treatment (see supplemental first aid instructions on this label).
P330 Rinse mouth.
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.
2.3 Hazards not otherwise classified (HNOC) or not covered by GHS - none
Section 3: Composition/information on ingredients
Substance information Substance name CAS No. EC No. Molecular formula Concentration
Minoxidil Sulphate 83701-22-8 C9H15N5O4S C9H15N5O4S ≥99%
Remark: The rest unspecified ingredients are impurities, and they are not hazard.
Section 4: First aid measures
4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed no data available
Section 5: Fire-fighting measures
5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture Carbon oxides, Hydrogen bromide gas
5.3 Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information no data available
Section 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section
6.2 Environmental precautions Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections For disposal see section 13.
Section 7: Handling and storage
7.1 Precautions for safe handling Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Section 8 : Exposure controls/personal protection
8.1 Control parameters Components with workplace control parameters Contains no substances with occupational exposure limit values.
8.2 Exposure controls Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure
Do not let product enter drains.
Section 9: Physical and chemical properties
9.1 General Information Appearance: White or almost white crystalline powder Odor: Odorless Solubility: Soluble in water, propylene glycol, sparingly soluble in methanol PH(3% w/v): 2.5 ~ 3.5 Loss on Drying ≤3.0% Residue on Ignition ≤0.5% Organic Volatile Impurities Methanol ≤3000ppm Ethanol ≤5000ppm Ethyl Acetate ≤5000ppm Heavy Metals≤20ppm Assay (HPLC) ≥99.0%
Section 10: Stability and reactivity
10.1 Reactivity no data available
10.2 Chemical stability Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions no data available
10.4 Conditions to avoid no data available
10.5 Incompatible materials Strong oxidizing agents
10.6 Hazardous decomposition products Other decomposition products - no data available In the event of fire: see section 5
Section 11: Toxicological information
11.1 Information on toxicological effects
no data available
Inhalation: no data available
Dermal: no data available no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitisation no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH.
NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.
Reproductive toxicity no data available no data available
Specific target organ toxicity - single exposure no data available
Section 12: Ecological information
12.1 Toxicity no data available
12.2 Persistence and degradability no data available
12.3 Bioaccumulative potential no data available
12.4 Mobility in soil no data available
12.5 Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Other adverse effects no data available
Section 13: Disposal considerations
13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product.
Section 14: Transport information
DOT (US) Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods
Section 15: Regulatory information
SARA 302 Components SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards No SARA Hazards Massachusetts Right To Know Components No components are subject to the Massachusetts Right to Know Act.
Pennsylvania Right To Know Components Minoxidil Sulphate CAS-No. 83701-22-8 Revision Date New Jersey Right To Know Components Minoxidil Sulphate CAS-No. 83701-22-8
Revision Date California Prop. 65 Components This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm
Section 16: Other information
Declare to reader The information in this Safety Data Sheet (SDS) was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This SDS was prepared and is to be used only for this product. If the product is used as a component in another product, this SDS information may not be applicable. According to REACH Article 31(5), the SDS shall be supplied in an official language of the Member State(s) where the substance or mixture is placed on the market, unless the recipient Member State(s) concerned provide otherwise. It should also be noted that this SDS is applicable to the countries with English as an official language.